LC and LC-MS/MS Studies for the Characterization of Forced Degradation Products of Tucatinib, a Novel Tyrosine Kinase Inhibitor
The happening, confirmation, and characterisation of compulsory shame products utilising LC-MS/MS were the main aims of the current study.Using an isocratic HPLC approach, tucatinib maybe calculated quantitatively at a intuitiveness of 239 nm in a natural, selective, justified, and clear tone. An isocratic elution of samples was acted on...
Read More
Determination of Immunological Characterization and Verification of Recombinant Streptococcal Protein G | Chapter 2 | New Visions in Biological Science Vol.10
The purpose of this study was to identify the immunological characterisation and verification of recombinant streptococcal protein G (rSPG), which is essential since it has a higher specificity for immunoglobulin (Ig) than staphylococcal protein A. However, the high expense of commercial recombinant (r) SPG has stymied further study into...
Read More
Research on Development and Optimization of an LC-MS/MS Method for Dosage Form of Ergocalciferol (Vitamin D2) in Human Plasma
The use of high-resolution mass spectra has made it easier to measure ergocalciferol in biological material. To quantify ergocalciferol, multiple LC-MS/MS methods have been developed. Using LC-MS/MS, researchers were able to establish an accurate method for quantifying ergocalciferol in a large number of samples, which should be tested in...
Read More
Development of Validated LC-MS/MS Method for Pharmacokinetic and Bioequivalence Studies of Azelastine in Korean Healthy Volunteers
The pharmacokinetic (PK) and bioequivalence (BE) studies of two formulations of azelastine (AZ) was carried out in 18 healthy male Korean volunteers according to a randomized crossover-design and were performed by a new validated liquid chromatography coupled to tandem mass spectrometry (LCMS/MS) method for quantitative analysis of plasma AZ....
Read More