Tag: heat pain

Thermo-TRP Channels in Pain Sensation: An Overview

The perception of temperature is a major component of sensory experience of animal and human organisms. A sensitive response of the nervous system to changes in temperature is of predominant importance for homeo-therms to maintain a stable body temperature. Recent investigations in central and peripheral thermosensitivity have emphasized the...
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TRP Channels in Physiological Nociception and Pain

The Transient Receptor Potential (TRP) channel superfamily is comprised of a large group of cation-permeable channels, which display an extraordinary diversity of functions from sensory signaling to animal behaviors. These channels are ‘cellular sensors’ that respond to changes in the cellular environment, including temperature, stretch/pressure, chemicals, oxidation/reduction, osmolarity and...
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