Characteristics of Haloperidol Interacting with Serum Albumins: A Study Using Computational Model
Using a computational model based on spectrofluorimetry data, the characteristics of haloperidol’s interaction with HSA and BSA at 25°C and 37°C were investigated. The relative locations of this drug’s major binding sites in albumins were calculated. Haloperidol is a neuroleptic medicine that belongs to the butyrophenone category. It is...
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Neuroleptic Malignant Syndrome: Looked at from the Diagnostic and Therapeutic Perspectives in a General Hospital Setting
Neuroleptic malignant syndrome is a rare life-threatening condition, usually induced by typical and atypical antipsychotics. A middle-aged woman with bipolar disorder and acute back pain due to multiple falls was admitted to the trauma ward of a general hospital. After 3 days, she suddenly developed signs and symptoms of...
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