Aspirin from Various Analgesic Formulations Using Titrimetry, UV Spectroscopic and HPLC Techniques: A Comparative Analysis
Because aspirin, also known as acetyl salicylic acid or 2-acetoxybenzoic acid, contains a carboxylic acid functional group, it is easier to measure using a strong alkali such as NaOH. Aspirin overdoses can have devastating consequences, including death and considerable morbidity. In most analgesic medication formulations in tablet form, aspirin...
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Acute-phase Treatment and Prevention of Large Coronary Artery Lesions in Kawasaki Disease
Kawasaki disease (KD) is a type of febrile systemic vasculitis that mostly affects children under the age of five. CALs, or coronary artery lesions, are a serious consequence of KD. However, there is no recognised acute-phase therapy for the prevention of high CALs and coronary artery stenosis induced by...
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Investigation on the Anti-Ulcerogenic Activity of Aqueous Extract of Unripe Fruit of Musa sapientum Linn in Combination with Vitamin C on Ulcer Induced Models in Experimental Rats
The aim of this study was to see how an aqueous extract of Musa sapientum Linn’s unripe fruit combined with Vitamin C affected aspirin and ethanol-induced ulcer models in Wistar rats. It’s a tropical plant whose fruit is commonly eaten as a healthy food all over the world. Anti-ulcer...
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Experiments on Micellar Liquid Chromatographic Method for Simultaneous Determination of Atenolol and Aspirin in Bulk and Pharmaceutical Dosage Form
Micellar liquid chromatographic method has been developed for the simultaneous determination of Atenolol and Aspirin in a bulk drug and pharmaceutical formulation. Chromatographic separation achieved isocratically on ODS hypersil C18 column (5 μm, 250 mm × 4.6 mm) and micellar mobile phase of 0.07M sodium dodecyl sulfate (SDS) pH...
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Stability Test of an Aspirin in the Aspirin+Curcumin Admixture at Different Storing Conditions
Aims: The pure stability of aspirin in the aspirin (100 μg/mL) only and aspirin (100 μg/mL)+curcumin(600 μg/mL) admixture without any ingredient under two solvents (distilled water, DW and normal saline, NS), three storage temperatures(25ºC, 4ºC and -20ºC) and periods (1st,3rdand 7thdays) was evaluated. Study Design: The injectable DW- and...
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Antidiabetic and Antiinflammatory Activity of Methanol and Aqueous Extracts of Pergularia daemia (Forssk.) Chiov.
The present study is aimed to investigate the antidiabetic and antiinflammatory activity of crude extracts (methanol and aqueous) of leaves of Pergularia daemia. The acute oral toxicity showed that the crude extracts of P. daemia leaf were safe until 2000 mg/kg body weight and no macroscopical organ abnormalities were...
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