Pharmacological Evaluation of Novel Quinazoline Derivatives for Their Anti-Convulsant and CNS Depressant Activities
The present study tried to design and synthesise isomeric new series of quinazoline-4-one/4-thione products, based on the pharmacophoric model of CNS action by structural modifications retaining the essential fundamental features for the exercise and evaluated for their anticonvulsant and CNS depressant features. Epilepsy, a disorder of unprovoked seizures is...
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Antimicrobial, Analgesic and Anti-inflammatory Activity of Some Synthesized Quinazoline Derivatives
Series of 7-chloro-3-[substituted (amino/phenyl amino)]-2-phenyl quinazolin-4(3H)-individual/thione derivatives and 1-(7-chloro-4-oxo/-2-phenylquinazoline-3 (4H-yl)) substituted urea derivatives were combined and characterised The reaction proceeds through the in-between 7-chloro-2-phenyl-4H-benzo[d] [1, 3] oxazin-4-one. Synthesized compounds were characterised from shade resembling such a color (IR), 1H nuclear magnetic reverberation (NMR) and mass spectra (m/z) and basic...
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Solid Lipid Nanoparticle: Technique of Drug Designing
This member focuses on a comprehensive review and itemized study of nanoparticles. Especially Solid lipid nanoparticles are rapidly developing field of nanotechnology accompanying several potential uses in drug delivery, dispassionate medicine and research in addition to in other varied sciences. Due to their singular size-contingent properties, lipid nanoparticles offer...
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