Eco-friendly and Green Synthesis of 2-alkylsulfanyl3H-quinazolin-4-one
Reaction of 2-Thioquinazolinone (1) with various alkylating agents like dimethyl sulphate (DMS), diethyl sulphate (DES) and benzyl chloride (PhCH2Cl) in the presence of K2CO3 as a mild base, by a simple physical grinding, microwave irradiation, and PEG-600 under solvent-free conditions for 10-15 min at RT, followed by processing,...
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