Tag: 1

The functional 1, 8-Naphthalimide derivatives that can attach to deoxyribonucleic acid (DNA) and have anticancer properties have gotten a lot of press recently. The synthesis of novel 1,8-Naphthalimides derivatives and their antibacterial properties are reported in this chapter. Author (S) Details Rambabu Sirgamalla Department of Chemistry, University College of...

Acetazolamide and Methazolamide are diuretic 1,3,4-thiadiazole compounds that are well-known. As a result, certain novel 2,5-disubstituted-1,3,4-thiadiazoles were synthesised and diuretic efficacy was tested. The diuretic action of a handful of the compounds, including IVa1, IVb2, and IVc2, was comparable to that of the conventional medication acetazolamide. The Osiris property...

A new series of 1, 3, 4-oxadiazoles (3a-j) was synthesised in this study by reacting INH (1) with substituted aromatic acids (2) in the presence of POCl3. IR, 1H NMR, and mass spectrum data were used to identify the novel compounds. In-vitro antibacterial and antifungal properties were tested on...

The corrosion inhibitory capacity of a synthetic heterocyclic molecule, namely 1, 3, 5-trimethyl-2, 6-diphenyl piperidin-4-one oxime, was evaluated using weight loss experiments, electrochemical methods, and SEM examinations in 1M hydrochloric acid (HCl) media against mild steel (MS) (TPO). The weight loss studies were conducted at three different temperatures for...

This article has have as objective one: Present of two new algorithm for its application in the computers, with they we will can know all and of each of values 2𝑛 in polynomial time not only the individual values of (n) if no all values of an interval =...

A straightforward method has been developed to synthesize new anti-inflammatory 1,7-dihydropyrazolo[3,4-d] imidazo[1,2-f] pyrimidine 5 from aminocyanopyrazole. These compounds were tested for anti-inflammatory, gastroprotective, analgesic, antioxidant, and anticandidal properties. After studying the structure-activity relationships, the compound 6-(4-methoxyphenyl)-3-methyl-1,7-dihydropyrazolo[3,4-d]imidazo[1,2-f]pyrimidine, 5a, was chosen as having the most potent activities. The structures of all...

One of the most important aspects of the manufacture of medicinal drugs is the synthesis of novel thiadiazoles. Current medicinal chemistry research has focused on the properties of new compounds with possible novel structural features and biological applications. In this context, the synthesis and characterization of 5-[substituted]-1, 3, 4-thiadiazol-2-amines...

A Quinolino novel series[3,2-f] [1,2,4] The [3,4-b] Triazolo [1,3,4] The Thiadiazepine (7a-i) derivatives incorporated with 3-(5–i) (benzofuran-2-yl) -1-phenyl-1H-3-yl pyrazol) Moiety was synthesised by a 5-(5-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-3-yl)) one-point cyclo-condensation reaction. -4-amino-4H-1,2,4-triazole-3-thiol (4) in the presence of K2CO3 in DMF with 2-chloro-quinoline-3-carbaldehyde derivatives (6a-i). Characterization of 3-(5-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-3-yl)-substituted quinolino [3,2-f] newly synthesised compounds...

The present study seeks to investigate the synthesis and structural characteristics of derivatives of Indanone, Tetralone and Naphthone. Via Claisen condensations, arylhydrazine condensations, BakerVenkataraman rearrangements, Claisen-Schmidt reactions, selective fluorinations and trifluoroacetylations in yields ranging from 22-92 percent, indanone, tetralone and naphthone derivatives and fused-ring heterocycles were prepared. Regiochemistry and...

As a continuation of our research on developing anticancer agents and based on the proven proprieties of thieno[2,3‐b]pyridines as anticancer, we have designed to synthesize novel thieno[2,3‐ b]pyridine derivatives that incorporate different biologically active heterocycles through various chemical reactions. All of the newly obtained compounds, compared with the standard...