Ethical Challenges of Biobanks and Pathology Research in Egypt

Background: Biobanking today plays a key tool in biomedical research. Establishment and proper running of biobanks in developing countries is confronted with a number of challenges of legal, ethical, and financial nature. Considering that there are no guidelines or regulations to control biobanking in Egypt;  major  ethical  issues  arise  and  are  often  managed  by  research  ethics  committees  (RECs). Pathologists are the custodians of tissue samples in different universities and hospitals; they have an important role in advancement of scientific research. So, they have to equip themselves adequately to manage the evolution of pathology work towards integration of biomarker analysis in clinical research and to deal with the ethical and legal issues of biobanks in Egypt.

Objective/Aim: The  purpose  of  this  review  is  to  highlight  the  current  situation  of  human  tissue research and biobanking in Egyptwith Comparative policy of other countries. We will address the role of pathologists and the difficulties and challenges facing the process of initiating biobanks and give some recommendations that might help different stakeholders for establishing biobanks in Egypt.

Conclusion: Egypt is one of the developing countries which are in need to implement biobanks to improve  the  quality  of  research.  The  review  highlights  the  different  challenges  facing  biobanks  in Egypt, mainly: lack of legislations, consent form, public trust, tissue transfer and commercialization. It also discuss the role of pathologists and research ethics committees in establishing and maintaining the work in these biobanks; and to make every effort for the interests of the participants, community and scientific progress, hopefully for good future of biomedical research in Egypt.

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