A Case Report and Literature Review on Familial Adenomatous Polyposis Coli in East Africa

The first paragraph is an introduction. In East Africa, familial adenomatous polyposis (FAP) is an unusual diagnosis. It occurs around puberty and is less common in females than in males. The author describes a case of a 21-year-old man who had blood-stained stool on occasion and was diagnosed with familial adenomatous polyposis coli. Following that, a study of the pathogenesis, clinical characteristics, and treatment options for FAP in East Africa is presented.

This patient presented with a rectal mass, blood soaked stool, and a clear family history of familial adenomatous polyposis. The procedure included a complete proctocolectomy and ileoanal anastomosis. This patient’s postoperative recovery was uneventful.

On the resected colorectal specimen, the usual gross pathological and histological features of familial adenomatous polyposis and rectal adenocarcinoma were visible. In addition, this research examines the literature on familial adenomatous polyposis coli’s clinical appearance, pathological characteristics, and treatment options.

Conclusion: In a young patient with a long family history of CRC, FAP should always be considered. Patients with early symptoms, as well as those with a long family history of FAP, may have a colonoscopy. A proctocolectomy and Brooke ileostomy would not be a suitable choice in a young patient in East Africa because the existence of a permanent stoma is considered unacceptable.

Author (s) Details

Richard Wismayer
Department of Surgery, Masaka Regional Referral Hospital, Masaka, Uganda and Department of Pathology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.

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