Editor Papa Research February 17, 2020

Subacute sclerosing panencephalitis (SSPE) is a progressive degenerative disease caused by measles infection with overall poor prognosis in spite multiple modalities of treatment. The course of the disease is characterized by progressive neurological decline in the form of behavioral and personality changes followed by a stage of characteristic periodic myoclonic spasms followed by a stage of quadriplegia movement disorder, vegetative state and frequently early death. Here we report two cases with atypical presentation of early rather than late movement disorder during illness and the unusual association of central precocious puberty preceding the course of illness in one of the cases.

Author(s) Details

Hanin Al-Gethami
Neuro-Science Center, King Fahd Medical City, Riyadh, Saudi Arabia

Mohammad Talal Alrifai
Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Ahmed Al-Rumayyan
Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Waleed Al-Tuwaijri
Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Duaa Ba-Armah
Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

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