Editor Papa Research July 23, 2019

Aims: Highly Active Antiretroviral Therapy (HAART) has changed the natural history of HIV infection, several adverse events may limit its efficacy. Antiretroviral drugs are associated with increased risk of severe hepatotoxicity. Homeopathy is a popular form of complementary and alternative medicine and is used to treat certain liver ailments. Chelidonium majus has a long history […]

Editor Papa Research July 23, 2019

Introduction: Routinely patients with hip or knee arthroplasty are transferred from acute clinic to rehabilitation department at an ever earlier stage (one week post-op). The  most  frequent  complications  after  lower  extremity  arthroplasty  are:  local  pain,  edema, contracture,  tardive  calcification,  infection,  hemorrhage,  pulmonary  embolism  and  deep  vein thrombosis. Sometimes unexpected complications can provoke a delay or […]

Editor Papa Research July 23, 2019

Aims: To find evidence that the immune response modifies behavior by regulating sex hormones. Study Design: Experimental transversal case control study and longitudinal experimental case control study. Place and Duration of Study: Biochemistry and Molecular Biology Chair, School of Medicine, Medical Sciences Faculty, National University of Córdoba. 2009-2015. Methodology: Albino Swiss mice Rockefeller strain (110) […]

Editor Papa Research July 23, 2019

Background: Patient-tested and -friendly  information leaflets provide  sufficient, accurate, and pertinent information about prescribed and over-the-counter medications to health consumers for their safety,  enhanced  satisfaction, improved  outcomes and no medication errors across the globe. However healthcare consumers’ knowledge, attitude, behaviour and perception concerning different items of drug leaflets differ across the board. Objective: This study […]

Editor Papa Research July 23, 2019

The  focus  of  traditional  prodrug  approach  was  on  altering  various  physiochemical  parameters, whereas the current modern computational approach considers designing prodrugs through attaching appropriate  linkers  with  drugs  having  poor  bioavailability  which  upon  exposure  to  physiological environments release the parent active drugs in a programmable (controlled) manner resulting in an improvement of their bioavailability. With the […]

Editor Papa Research July 23, 2019

Possibility of occurrence of drug interactions increases with the number of drugs administered. Drug interactions can be classified in a number of ways using different basis as well as terminology. Drugs may interact with other drugs, foods, beverages, contrast media, and herbs; outside or inside the body. The term “drug-condition interaction” is sometimes used when […]

Editor Papa Research July 23, 2019

Aims: Recent research indicates that plant molecules, particularly those that are rich with antioxidant, anti-inflammatory and immune modulatory  constituents, can modify and prevent  the detrimental effects of gasoline compounds on reproductive endpoints. However, whether C. citratusdecoction can alleviate gasoline vapour (GV)-induced derangement of female reproductive hormones has not yet been documented. In this study, the […]

Editor Papa Research July 23, 2019

Aims: To evaluate the efficacy of two alkylating structural analogues of chloramphenicol that have potential for application for treatment of dermal sited neoplasms. Study Design: Two compounds have been shown to alkylate guanosine-5’-diphosphate (GDP) at physiological conditions. These same compounds are evaluated for dermal penetration based on Kp and compared to other alkylating agents applied […]